1Ls, do what you can to schedule fall 2L classes with one day off. I'd recommend Monday. First, the ability to have a day off is one not to be wasted. It's not going to happen in the real world. Second, it makes OCI easier.
I have Fridays off, which is great, but so do half of all 2Ls doing OCI, it seems. This means Friday callbacks are scarce (plus, some attorneys prefer not to schedule interviews on Fridays), so you miss more class on the days you have classes.
Regardless of how you plan it, you will probably be behind after OCI, if you do it, but minimizing the amount of missed class is preferable.